Etazene Etodesnitazene Powder (also known as desnitroetonitazene, etazen, etazene, and etazone) is a benzimidazole-derived opioid analgesic drug, which was originally developed in the late 1950s alongside etonitazene and a range of related derivatives.[1] It is many times less potent than etonitazene itself, but still 70 times more potent than morphine in animal studies. Corresponding analogues where the N,N-diethyl group is replaced by piperidine or pyrrolidine rings also retain significant activity (10 times and 20 times morphine, respectively).[2] Etodesnitazene has been sold as a designer drug,[3] first being identified in both Poland and Finland in March 2020.[4][5]
Legal Status
United Kingdom
Since 15 January 2025 it is covered by the UK’s generic definition on 2-benzyl benzimidazole derived opioids[6][7] because it contains the 2-(2-benzyl-benzimidazol-1-yl)ethanamine backbone with only the following modification:[8]
- The phenyl ring of the benzyl system is substituted by an alkoxy group containing two carbon atoms.
See also
- Brorphine
- Etonitazepyne
- Etoacetazene
- Etocyanazene
- Etomethazene
- Isotonitazene
- Metonitazene
- Metodesnitazene
- Protodesnitazene
- MCHB-1
- List of benzimidazole opioids
